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Ottavia Spiga
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2020 – today
- 2022
- [j11]Vittoria Cicaloni, Malancha Karmakar, Luisa Frusciante, Francesco Pettini, Anna Visibelli, Maurizio Orlandini, Federico Galvagni, Maurizio Mongiat, Michael Silk, Federica Nardi, David B. Ascher, Annalisa Santucci, Ottavia Spiga:
Bioinformatics Approaches to Predict Mutation Effects in the Binding Site of the Proangiogenic Molecule CD93. Frontiers Bioinform. 2 (2022) - [j10]Pietro Bongini, Neri Niccolai, Alfonso Trezza, Guido Mangiavacchi, Annalisa Santucci, Ottavia Spiga, Monica Bianchini, Simone Gardini:
Structural Bioinformatic Survey of Protein-Small Molecule Interfaces Delineates the Role of Glycine in Surface Pocket Formation. IEEE ACM Trans. Comput. Biol. Bioinform. 19(3): 1881-1886 (2022) - 2021
- [j9]Ottavia Spiga, Vittoria Cicaloni, Giovanna Maria Dimitri, Francesco Pettini, Daniela Braconi, Andrea Bernini, Annalisa Santucci:
Machine learning application for patient stratification and phenotype/genotype investigation in a rare disease. Briefings Bioinform. 22(5) (2021) - [j8]Pietro Bongini, Simone Gardini, Monica Bianchini, Ottavia Spiga, Neri Niccolai:
Structural bioinformatics survey on disease-inducing missense mutations. J. Bioinform. Comput. Biol. 19(3): 2150008:1-2150008:15 (2021) - 2020
- [j7]Andrea Bernini, Silvia Galderisi, Ottavia Spiga, Chukwudi Onyekachi Amarabom, Annalisa Santucci:
Transient pockets as mediators of gas molecules routes inside proteins: The case study of dioxygen pathway in homogentisate 1, 2-dioxygenase and its implication in Alkaptonuria development. Comput. Biol. Chem. 88: 107356 (2020) - [j6]Alberto Rossi, Giorgia Giacomini, Vittoria Cicaloni, Silvia Galderisi, Maria Serena Milella, Andrea Bernini, Lia Millucci, Ottavia Spiga, Monica Bianchini, Annalisa Santucci:
AKUImg: A database of cartilage images of Alkaptonuria patients. Comput. Biol. Medicine 122: 103863 (2020)
2010 – 2019
- 2018
- [j5]Ottavia Spiga, Vittoria Cicaloni, Andrea Zatkova, Lia Millucci, Giulia Bernardini, Andrea Bernini, Barbara Marzocchi, Monica Bianchini, Andrea Zugarini, Alberto Rossi, Matteo Zazzeri, Alfonso Trezza, Bruno Frediani, Lakshminarayan Ranganath, Daniela Braconi, Annalisa Santucci:
A new integrated and interactive tool applicable to inborn errors of metabolism: Application to alkaptonuria. Comput. Biol. Medicine 103: 1-7 (2018) - 2017
- [j4]Andrea Bernini, Silvia Galderisi, Ottavia Spiga, Giulia Bernardini, Neri Niccolai, Fabrizio Manetti, Annalisa Santucci:
Toward a generalized computational workflow for exploiting transient pockets as new targets for small molecule stabilizers: Application to the homogentisate 1, 2-dioxygenase mutants at the base of rare disease Alkaptonuria. Comput. Biol. Chem. 70: 133-141 (2017) - [j3]Ottavia Spiga, Vittoria Cicaloni, Andrea Bernini, Andrea Zatkova, Annalisa Santucci:
ApreciseKUre: an approach of Precision Medicine in a Rare Disease. BMC Medical Informatics Decis. Mak. 17(1): 42:1-42:5 (2017) - 2013
- [j2]Silvia Bottini, Andrea Bernini, Matteo De Chiara, Diego Garlaschelli, Ottavia Spiga, Marco Dioguardi, Elisa Vannuccini, Anna Tramontano, Neri Niccolai:
ProCoCoA: A quantitative approach for analyzing protein core composition. Comput. Biol. Chem. 43: 29-34 (2013)
2000 – 2009
- 2005
- [j1]Daniele Varrazzo, Andrea Bernini, Ottavia Spiga, Arianna Ciutti, Stefano Chiellini, Vincenzo Venditti, Luisa Bracci, Neri Niccolai:
Three-dimensional computation of atom depth in complex molecular structures. Bioinform. 21(12): 2856-2860 (2005)
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